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Chemical Structure : LY3027788
Catalog No.: PC-60731Not For Human Use, Lab Use Only.
LY3027788 is an orally active prodrug of LY3020371, which is a potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, respectively.
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LY3027788 is an orally active prodrug of LY3020371, which is a potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, respectively.
LY3027788 augments the antidepressant-like effects of fluoxetine or citalopram without altering plasma or brain levels of these compounds.
| M.Wt | 591.576 | |
| Formula | C25H31F2NO11S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Witkin JM, et al. J Pharmacol Exp Ther. 2017 Apr;361(1):68-86.
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