LY3499446 | KRAS G12C inhibitor | Probechem Biochemicals

Chemical Structure : LY3499446

Catalog No.: PC-22826Not For Human Use, Lab Use Only.

LY3499446 is a potent, selective inhibitor of KRAS G12C.

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Biological Activity

LY3499446 is a potent, selective inhibitor of KRAS G12C.

M.Wt	486.93
Formula	C22H17ClF2N6OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-[4-[7-(2-amino-7-fluoro-1,3-benzothiazol-4-yl)-6-chloro-8-fluoroquinazolin-4-yl]piperazin-1-yl]prop-2-en-1-one

1. Chendi Li, et al. Cancer Res (2023) 83 (7_Supplement): 3868.