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LY3499446 mesylate

Chemical Structure : LY3499446 mesylate

CAS No.: 2409131-51-5

LY3499446 mesylate (LY-3499446 mesylate)

Catalog No.: PC-22827Not For Human Use, Lab Use Only.

LY3499446 mesylate is a potent, selective inhibitor of KRAS G12C.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

LY3499446 mesylate is a potent, selective inhibitor of KRAS G12C.

Physicochemical Properties

M.Wt 583.03
Formula C23H21ClF2N6O4S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Propen-1-one, 1-[4-[7-(2-amino-7-fluoro-4-benzothiazolyl)-6-chloro-8-fluoro-4-quinazolinyl]-1-piperazinyl]-, methanesulfonate (1:1)

References

1. Chendi Li, et al. Cancer Res (2023) 83 (7_Supplement): 3868.

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