LY367385

Chemical Structure : LY367385

CAS No.: 198419-91-9

Catalog No.: PC-23780Not For Human Use, Lab Use Only.

LY367385 is a potent, highly selective mGluR1 antagonis with IC50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, shows no activity against mGluR5.

Packing	Price	Stock
5 mg	$248	In stock
10 mg	$388	In stock
25 mg	$598	In stock
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Biological Activity

LY367385 is a potent, highly selective mGluR1 antagonis with IC50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, shows no activity against mGluR5.

Physicochemical Properties

M.Wt	209.20
Formula	C10H11NO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-4-(Amino(carboxy)methyl)-3-methylbenzoic acid

References

1. Sergueeva OA, et al. Neuropharmacology. 1993 Sep;32(9):933-5.

2. Eaton SA, et al. Eur J Pharmacol. 1993 Jan 15;244(2):195-7.

3. lark et al. Bioorg.Med.Chem.Lett. November 1997, 7 (21): 2777-2780.

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LY367385

Biological Activity

Physicochemical Properties

References

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