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Chemical Structure : LY379196
Catalog No.: PC-62078Not For Human Use, Lab Use Only.
LY379196 is a highly specific PKCβ inhibitor with IC50 of 30-50 nM for PKCβI and PKCβII, displays >10-fold selectivity of PKCα, δ, η, and γ (>600 nM).
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LY379196 is a highly specific PKCβ inhibitor with IC50 of 30-50 nM for PKCβI and PKCβII, displays >10-fold selectivity of PKCα, δ, η, and γ (>600 nM).
LY379196 blocks TPA-induced monocytic differentiation of HL60 cells.
| M.Wt | ||
| Formula | C29H30N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jirousek MR, et al. J Med Chem. 1996 Jul 5;39(14):2664-71.
2. Slosberg ED, et al. Mol Carcinog. 2000 Mar;27(3):166-76.
3. Tabit CE, et al. Circulation. 2013 Jan 1;127(1):86-95.
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