Chemical Structure : Laforin inhibitor 9c
Catalog No.: PC-24364Not For Human Use, Lab Use Only.
Laforin inhibitor 9c is a highly potent, selective inhibitor of glycogen phosphatase laforin with IC50 of 4.0 nM and Ki value of 1.9 nM, >8000-fold selective over other 15 PTPs.
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Laforin inhibitor 9c is a highly potent, selective inhibitor of glycogen phosphatase laforin with IC50 of 4.0 nM and Ki value of 1.9 nM, >8000-fold selective over other 15 PTPs.
Laforin inhibitor 9c efficiently blocks laforin-mediated glucan dephosphorylation inside the cell and possess favorable pharmacokinetic properties in mice.
M.Wt | 586.06 | |
Formula | C28H28ClN3O7S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Lin J, et al. J Med Chem. 2025 Apr 16. doi: 10.1021/acs.jmedchem.4c02580.
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