Lalistat-1

Chemical Structure : Lalistat-1

CAS No.: 501104-16-1

Catalog No.: PC-20890Not For Human Use, Lab Use Only.

Lalistat 1 is a potent and selective lysosomal acid lipase (LAL) inhibitor with IC50 of 68 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase.

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5 mg	$188	In stock
25 mg	$358	In stock
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Biological Activity

Lalistat 1 is a potent and selective lysosomal acid lipase (LAL) inhibitor with IC50 of 68 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase.
Lalistat 1 interferes with neutral lipolysis.
Lalistat 1 binds to active center of neutral lipid hydrolases.

Physicochemical Properties

M.Wt	298.36
Formula	C12H18N4O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	O=C(OC1=NSN=C1N2CCCCC2)N3CCOCC3

References

1. Bradić I, et al. Mol Metab. 2022 Jul;61:101510.

2. Hamilton J, et al. Clin Chim Acta. 2012 Aug 16;413(15-16):1207-10.

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Lalistat-1

Biological Activity

Physicochemical Properties

References

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