Latrunculin B

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Chemical Structure : Latrunculin B

CAS No.: 76343-94-7

Catalog No.: PC-27619Not For Human Use, Lab Use Only.

Latrunculin B is an antimicrobial marine alkaloid and actin polymerization inhibitor, disrupts microfilament organization and affects cell growth, sequesters monomeric G-actin, leading to the disassembly of actin filaments in cells.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	421.55
Formula	C22H31NO5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-4-((1R,4Z,8Z,10S,13R,15R)-15-Hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-dien-15-yl)thiazolidin-2-one

References

1. Yen-Yu Lu, et al. Clin Sci (Lond). 2016 May;130(9):721-32.

2. Schatten G, et al. Exp Cell Res. 1986 Sep;166(1):191-208.

3. Lewis CM, et al. Cancer Res. 1998 Jul 15;58(14):2952-6.

4. Spector I, et al. Cell Motil Cytoskeleton. 1989;13(3):127-44.

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Latrunculin B

Biological Activity

Physicochemical Properties

References

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