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Chemical Structure : Legumain inhibitor 10t
Catalog No.: PC-20813Not For Human Use, Lab Use Only.
Legumain inhibitor 10t is a potent, selective and cellularly active Legumain (asparagine endopeptidase, AEP) inhibitor with IC50 of 71 nM.
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Legumain inhibitor 10t is a potent, selective and cellularly active Legumain (asparagine endopeptidase, AEP) inhibitor with IC50 of 71 nM.
Legumain inhibitor 10t blocks colony formation in both metastatic breast (MCF7) and prostate (PC3) cancer cell lines with IC50 of 5 and 2.5 uM, respectively.
| M.Wt | 482.60 | |
| Formula | C25H30N4O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kerry A Ness, et al. Bioorg Med Chem Lett. 2015 Dec 1;25(23):5642-5.
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