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Chemical Structure : Leriglitazone
Catalog No.: PC-49255Not For Human Use, Lab Use Only.
MIN-102 (Leriglitazone) is a novel brain penetrant, selective and orally bioavailable PPARγ agonist with a potential best-in-class profile indicated for CNS diseases.
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MIN-102 (Leriglitazone) is a novel brain penetrant, selective and orally bioavailable PPARγ agonist with a potential best-in-class profile indicated for CNS diseases.
MIN-102 (Leriglitazone) increases frataxin levels and mitochondrial markers in FRDA models.
MIN-102 (Leriglitazone) protects from neurodegeneration by improving mitochondrial function.
MIN-102 (Leriglitazone) prevents lipid droplets formation in frataxin-deficient cardiomyocytes.
MIN-102 (Leriglitazone) rescues the motor function deficit of the YG8sR mice.
MIN-102 (Leriglitazone) emerges as a potential therapeutic agent for Friedreich Ataxia.
| M.Wt | 372.439 | |
| Formula | C19H20N2O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Laura Rodríguez-Pascau, et al. Neurobiol Dis. 2021 Jan;148:105162.
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