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Licancopan

Chemical Structure : Licancopan

CAS No.: 2792727-20-7

Licancopan (HRS-5965, HRS5965)

Catalog No.: PC-26333Not For Human Use, Lab Use Only.

Licancopan (HRS-5965) is a potent, selective and orally active complement factor (Factor B) inhibitor, disrupts the formation of C3 convertases within the alternative pathway, thereby halting C3 cleavage and downstream complement activation.

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    Biological Activity

    Licancopan (HRS-5965) is a potent, selective and orally active complement factor (Factor B) inhibitor, disrupts the formation of C3 convertases within the alternative pathway, thereby halting C3 cleavage and downstream complement activation.

    Physicochemical Properties

    M.Wt 448.56
    Formula C27H32N2O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    Benzoic acid, 4-[(1S,3S,5R)-3-ethoxy-8-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]-8-azabicyclo[3.2.1]oct-1-yl]-

    References

    1. Patent WO2022143845 A1.

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