Chemical Structure : Licochalcone E
CAS No.: 864232-34-8
Catalog No.: PC-23581Not For Human Use, Lab Use Only.
Licochalcone E (LicoE) is a glycyrrhiza-inflata-derived chalcone, exhibits potent anti-inflammatory properties inhibits Aβ1-42 aggregation and activates Nrf2, also inhibits pancreatic lipase (PL) with IC50 of 5.8 uM.
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Licochalcone E (LicoE) is a glycyrrhiza-inflata-derived chalcone, exhibits potent anti-inflammatory properties inhibits Aβ1-42 aggregation and activates Nrf2, also inhibits pancreatic lipase (PL) with IC50 of 5.8 uM.
Licochalcone E displays high efficiency against methicillin-resistant Staphylococcus aureus (MRSA).
Licochalcone E activates Nrf2/antioxidant response element signaling pathway in both neuronal and microglial cells.
Licochalcone E suppresses lung metastasis in the 4T1 mammary orthotopic cancer model.
Licochalcone E improves insulin sensitivity in palmitic acid-treated HepG2 cells through inhibition of the NLRP3 signaling pathway.
M.Wt | 338.40 | |
Formula | C21H22O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(S,E)-3-(4-Hydroxy-2-methoxy-5-(3-methylbut-3-en-2-yl)phenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one |
1. Kim SS, et al. J Nutr Biochem. 2012 Oct;23(10):1314-23.
2. Zhou T, et al. J Microbiol Biotechnol. 2012 Jun;22(6):800-5.
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