Chemical Structure : Lipid L319
CAS No.: 1351586-50-9
Catalog No.: PC-38046Not For Human Use, Lab Use Only.
L-319 (O-8670) is an ionizable (pKa = 6.38) and biodegradable lipid that has been used in the formation of lipid nanoparticles.
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L-319 (O-8670) is an ionizable (pKa = 6.38) and biodegradable lipid that has been used in the formation of lipid nanoparticles.
Administration of mouse factor VII-targeting siRNA in L-319-containing lipid nanoparticles induces factor VII silencing in mice.
M.Wt | 678.052 | |
Formula | C41H75NO6 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1-((E)-non-1-en-1-yl) 17-((E)-non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate |
1. Martin A Maier, et al. Mol Ther. 2013 Aug;21(8):1570-8.
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