Lipid L319 |CAS:1351586-50-9 Probechem Biochemicals

Chemical Structure : Lipid L319

CAS No.: 1351586-50-9

Lipid L319 (O-8670, L-319)

Catalog No.: PC-38046Not For Human Use, Lab Use Only.

L-319 (O-8670) is an ionizable (pKa = 6.38) and biodegradable lipid that has been used in the formation of lipid nanoparticles.

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10 mg	$158	In stock
25 mg	$258	In stock
50 mg	$398	In stock
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Biological Activity

L-319 (O-8670) is an ionizable (pKa = 6.38) and biodegradable lipid that has been used in the formation of lipid nanoparticles.
Administration of mouse factor VII-targeting siRNA in L-319-containing lipid nanoparticles induces factor VII silencing in mice.

Physicochemical Properties

M.Wt	678.052
Formula	C41H75NO6
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-((E)-non-1-en-1-yl) 17-((E)-non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate

References

1. Martin A Maier, et al. Mol Ther. 2013 Aug;21(8):1570-8.

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Lipid L319 (O-8670, L-319)

Biological Activity

Physicochemical Properties

References

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