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Chemical Structure : Losartan
CAS No.: 114798-26-4
Catalog No.: PC-45316Not For Human Use, Lab Use Only.
Losartan (DuP-753) is a selective, competitive angiotensin II receptor type 1 (AT1) antagonist (IC50=20 nM) for treatment of high blood pressure (hypertension), also inhibits PAX8 expression and function.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 g | $58 | In stock | |
| 5 g | $98 | In stock | |
| 10 g | Get quote |
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Losartan (DuP-753) is a selective, competitive angiotensin II receptor type 1 (AT1) antagonist (IC50=20 nM) for treatment of high blood pressure (hypertension), also inhibits PAX8 expression and function.
| M.Wt | 422.9106 | |
| Formula | C22H23ClN6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- |
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1. Burnier, M. Circulation, 2001. 103(6): p. 904-12.
2. Ashry, O., et al. Respir Physiol Neurobiol, 2014.
3. Habashi, J.P., et al. Science, 2006. 312(5770): p. 117-21.
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