Chemical Structure : Losartan potassium
CAS No.: 124750-99-8
Catalog No.: PC-45317Not For Human Use, Lab Use Only.
A selective, competitive angiotensin II receptor type 1 (AT1) antagonist (IC50=20 nM) for treatment of high blood pressure (hypertension)..
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A selective, competitive angiotensin II receptor type 1 (AT1) antagonist (IC50=20 nM) for treatment of high blood pressure (hypertension).
Hypertension
Approved
M.Wt | 461.001 | |
Formula | C22H22ClKN6O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, potassium salt (1:1) |
1. Burnier, M. Circulation, 2001. 103(6): p. 904-12.
2. Ashry, O., et al. Respir Physiol Neurobiol, 2014.
3. Habashi, J.P., et al. Science, 2006. 312(5770): p. 117-21.
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