Losartan potassium |CAS:124750-99-8 Probechem Biochemicals

Chemical Structure : Losartan potassium

CAS No.: 124750-99-8

Catalog No.: PC-45317Not For Human Use, Lab Use Only.

A selective, competitive angiotensin II receptor type 1 (AT1) antagonist (IC50=20 nM) for treatment of high blood pressure (hypertension)..

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Biological Activity

A selective, competitive angiotensin II receptor type 1 (AT1) antagonist (IC50=20 nM) for treatment of high blood pressure (hypertension).

Hypertension

Approved

M.Wt	461.001
Formula	C22H22ClKN6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, potassium salt (1:1)

1. Burnier, M. Circulation, 2001. 103(6): p. 904-12.

2. Ashry, O., et al. Respir Physiol Neurobiol, 2014.

3. Habashi, J.P., et al. Science, 2006. 312(5770): p. 117-21.