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Chemical Structure : Luzindole
CAS No.: 117946-91-5
Catalog No.: PC-23430Not For Human Use, Lab Use Only.
Luzindole (N-0774) is a potent, selective melatonin receptor antagonist with Ki of 10.2 nM and 158 nM for human MT2 and MT1, respectively.
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Luzindole (N-0774) is a potent, selective melatonin receptor antagonist with Ki of 10.2 nM and 158 nM for human MT2 and MT1, respectively.
Luzindole (N-0774) shows anti-immobility effect and exerts antidepressant-like activity in the C3H/HeN mouse by antagonizing the action of endogenous hormone.
| M.Wt | 292.38 | |
| Formula | C19H20N2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(2-(2-Benzyl-1H-indol-3-yl)ethyl)acetamide |
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1. Dubocovich ML, et al. Eur J Pharmacol. 1990 Jul 3;182(2):313-25.
2. Dubocovich ML. J Pharmacol Exp Ther. 1988 Sep;246(3):902-10.
3. Constantinescu CS, et al. 1997;65(4):190-4.
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