MAC1 |CAS:325970-42-1 Probechem Biochemicals

Chemical Structure : MAC1

MAC1 (Monastrol Antagonizing Compound 1)

Catalog No.: PC-62405Not For Human Use, Lab Use Only.

MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity.

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Biological Activity

MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity.
MAC1 induces the formation of additional microtubule nucleation centers, which allows kinesin Kif15-dependent bipolar spindle assembly in the absence of Eg5 activity.

Physicochemical Properties

M.Wt	247.338
Formula	C15H21NO2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-1-(1-hydroxycyclohexyl)-3-phenylpropan-1-one oxime

References

1. Al-Obaidi N, et al. ACS Chem Biol. 2016 Jun 17;11(6):1544-51.

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MAC1 (Monastrol Antagonizing Compound 1)

Biological Activity

Physicochemical Properties

References

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