MASP-2, MASP-3 dual inhibitor 45

Chemical Structure : MASP-2, MASP-3 dual inhibitor 45

Catalog No.: PC-24088Not For Human Use, Lab Use Only.

MASP-2, MASP-3 dual inhibitor 45 is a potent, dual inhibitor of mannan-binding lectin-associated serine protease MASP-2 and MASP-3 with IC50 of 7.5 nM and 33 nM respectively.

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Biological Activity

MASP-2, MASP-3 dual inhibitor 45 is a potent, dual inhibitor of mannan-binding lectin-associated serine protease MASP-2 and MASP-3 with IC50 of 7.5 nM and 33 nM respectively.

Physicochemical Properties

M.Wt	491.57
Formula	C25H25N5O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(2-amino-1H-imidazole-4-yl)-3-methoxybenzyl)-2-(4-(phenylsulfonamido)phenyl) acetamide

References

1. Nakhla MC, et al. Eur J Med Chem. 2025 Jan 9;289:117238.

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