MBTP-15324 | PRODH inhibitor | Probechem Biochemicals

Chemical Structure : MBTP-15324

MBTP-15324 (MBTP15324)

Catalog No.: PC-27843Not For Human Use, Lab Use Only.

MBTP-15324 is an allosteric inhibitor of proline dehydrogenase (PRODH) with Kd of 1.45 uM, significantly attenuates cell viability, colony formation, and migration in PRODH-overexpressing lung cancer cells (A549 and LLC).

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Biological Activity

MBTP-15324 is an allosteric inhibitor of proline dehydrogenase (PRODH) with Kd of 1.45 uM, significantly attenuates cell viability, colony formation, and migration in PRODH-overexpressing lung cancer cells (A549 and LLC).

Physicochemical Properties

M.Wt	386.47
Formula	C20H22N2O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-hydroxy-1-(2-((2-hydroxyethyl)amino)ethyl)-4-(4-methylbenzoyl)-5-(thiophen-2-yl)-1,5-dihydro-2H-pyrrol-2-one

References

1. Yuxuan Zhou, et al. J Enzyme Inhib Med Chem. 2026 Dec;41(1):2719719.

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MBTP-15324 (MBTP15324)

Biological Activity

Physicochemical Properties

References

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