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Chemical Structure : MBX-2366
Catalog No.: PC-49003Not For Human Use, Lab Use Only.
MBX-2366 (ISG-21) is a potent and specific antimalarial compound with IC50 of 3 nM (P. falciparum growth inhibition), acts directly on plasmodial surface anion channel (PSAC, Target K0.5=2 nM) to quantitatively abolish parasite-induced permeability changes.
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MBX-2366 (ISG-21) is a potent and specific antimalarial compound with IC50 of 3 nM (P. falciparum growth inhibition), acts directly on plasmodial surface anion channel (PSAC, Target K0.5=2 nM) to quantitatively abolish parasite-induced permeability changes.
| M.Wt | 430.541 | |
| Formula | C20H22N4O3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Michelle M Butler, et al. Mol Pharmacol. 2022 Jul 7;MOLPHARM-AR-2022-000549.
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