MC3215 (MC-3215)

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Chemical Structure : MC3215

CAS No.: 2848613-22-7

Catalog No.: PC-25602Not For Human Use, Lab Use Only.

MC3215 (MC-3215) is a specific, cellular active small molecule activator of mitochondrial SIRT5 with binding KD of 28 uM, increases in vitro Sirt5 deacetylase activity and elicits similar effects to Sirt5 overexpression.

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2 mg	$218	In stock
5 mg	$358	In stock
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Biological Activity

MC3215 (MC-3215) is a specific, cellular active small molecule activator of mitochondrial SIRT5 with binding KD of 28 uM, increases in vitro Sirt5 deacetylase activity and elicits similar effects to Sirt5 overexpression.

Physicochemical Properties

M.Wt	411.47
Formula	C22H21NO5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	diethyl 1-benzoyl-4-(thiophen-3-yl)-1,4-dihydropyridine-3,5-dicarboxylate

References

1. Suenkel B, et al. J Med Chem. 2022 Oct 27;65(20):14015-14031.

2. Carola Castiello, et al. Drug Des Devel Ther. 2025 Jun 27:19:5489-5505.

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MC3215 (MC-3215)

Biological Activity

Physicochemical Properties

References

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