Catalog No.: PC-60554Not For Human Use, Lab Use Only.
ME-344 (NV-344) is a novel mitochondrial and mTOR inhibitor with potent anti-cancer activity, inhibits leukemia cell lines with IC50 of 70-260 nM, also targets heme oxygenase 1 (HO-1) and disrupts redox homeostasis.
ME-344 (NV-344) is a novel mitochondrial and mTOR inhibitor with potent anti-cancer activity, inhibits leukemia cell lines with IC50 of 70-260 nM, also targets heme oxygenase 1 (HO-1) and disrupts redox homeostasis.
ME-344 inhibits oxygen consumption rates, with specific effects on the respiratory chain, causes complex, redox-specific, and mitochondria-targeted effects in lung cancer cells.
ME-344 reduces tumor growth in OCI-AML2 xenograft models.
ME-344 is an active metabolite of NV-128.
