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Chemical Structure : MEK4 inhibitor 10e
Catalog No.: PC-72689Not For Human Use, Lab Use Only.
MEK4 inhibitor 10e is potent, selective cell permeable MEK4 inhibitor with IC50 of 61 nM.
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MEK4 inhibitor 10e is potent, selective MEK4 inhibitor with IC50 of 61 nM.
MEK4 inhibitor 10e demonstrated significant reduction of phospho-JNK and antiproliferative properties against pancreatic cancer cell lines, molecular inhibition of MEK4 pathway activates the MEK1/2 pathway.
MEK4 inhibitor 10e demonstrated synergistic effects against pancreatic cancer cells with the combination of MEK1/2 inhibitors.
| M.Wt | 291.3 | |
| Formula | C13H10FN3O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kwong AJ, et al. ACS Med Chem Lett. 2021 Sep 15;12(10):1559-1567.
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