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Chemical Structure : MEK4 inhibitor 15o
Catalog No.: PC-72692Not For Human Use, Lab Use Only.
MEK4 inhibitor 15o is potent, selective, cell permeable MEK4 inhibitor with IC50 of 83 nM.
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MEK4 inhibitor 15o is potent, selective, cell permeable MEK4 inhibitor with IC50 of 83 nM.
MEK4 inhibitor 10e demonstrated significant reduction of phospho-JNK and antiproliferative properties against pancreatic cancer cell lines, molecular inhibition of MEK4 pathway activates the MEK1/2 pathway.
MEK4 inhibitor 10e demonstrated synergistic effects against pancreatic cancer cells with the combination of MEK1/2 inhibitors.
| M.Wt | 410.423 | |
| Formula | C20H15FN4O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kwong AJ, et al. ACS Med Chem Lett. 2021 Sep 15;12(10):1559-1567.
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