MEK4 inhibitor 6ff

Chemical Structure : MEK4 inhibitor 6ff

Catalog No.: PC-72695Not For Human Use, Lab Use Only.

MEK4 inhibitor 6ff is potent, selective MEK4 inhibitor with IC50 of 66 nM.

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Biological Activity

MEK4 inhibitor 6ff is potent, selective MEK4 inhibitor with IC50 of 66 nM.
MEK4 inhibitor 6ff displays excellent selectivity across the entire MEK family, 150-fold more potent against MEK4 than any other MEKkinase, and is at least 385-fold selective against three other MEK kinases.

Physicochemical Properties

M.Wt	256.236
Formula	C14H9FN2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(6-fluoro-2H-indazol-3-yl)benzoic acid

References

1. Kristine K Deibler, et al. ChemMedChem. 2019 Mar 22;14(6):615-620.

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