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MEK4 inhibitor 6ff

Chemical Structure : MEK4 inhibitor 6ff

CAS No.: 2570386-33-1

MEK4 inhibitor 6ff

Catalog No.: PC-72695Not For Human Use, Lab Use Only.

MEK4 inhibitor 6ff is potent, selective MEK4 inhibitor with IC50 of 66 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MEK4 inhibitor 6ff is potent, selective MEK4 inhibitor with IC50 of 66 nM.
MEK4 inhibitor 6ff displays excellent selectivity across the entire MEK family, 150-fold more potent against MEK4 than any other MEKkinase, and is at least 385-fold selective against three other MEK kinases.

Physicochemical Properties

M.Wt 256.236
Formula C14H9FN2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(6-fluoro-2H-indazol-3-yl)benzoic acid

References

1. Kristine K Deibler, et al. ChemMedChem. 2019 Mar 22;14(6):615-620.

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