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Chemical Structure : METTL3 inhibitor 54
Catalog No.: PC-21078Not For Human Use, Lab Use Only.
METTL3 inhibitor 54 is a potent, selective inhibitor of m6A-RNA writer enzyme methyltransferase-like 3 (METTL3) with IC50 of 54 nM for METTL3/METTL14 in HTRF assays.
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METTL3 inhibitor 54 is a potent, selective inhibitor of m6A-RNA writer enzyme methyltransferase-like 3 (METTL3) with IC50 of 54 nM for METTL3/METTL14 in HTRF assays.
METTL3 inhibitor 54 displays no activity against METTL1 and METTL16 up to 200 μM.
METTL3 inhibitor 54 shows a GI50 of 6 μM for the MOLM-13 AML cell line.
| M.Wt | 590.82 | |
| Formula | C37H46N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Bedi RK, et al. ACS Bio Med Chem Au. 2023 Jun 14;3(4):359-370.
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