MI-1851 | Furin inhibitor | Probechem Biochemicals

Chemical Structure : MI-1851

CAS No.: 2417283-44-2

Catalog No.: PC-26214Not For Human Use, Lab Use Only.

MI-1851 is a highly potent, peptidic mimetic inhibitor of furin with Ki of 10.1 pM, inhibits SARS-CoV-2 replication.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MI-1851 is a highly potent, peptidic mimetic inhibitor of furin with Ki of 10.1 pM, inhibits SARS-CoV-2 replication.

M.Wt	767.90
Formula	C34H53N15O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-((S)-1-((4-carbamimidoylbenzyl)amino)-4-(guanidinooxy)-1-oxobutan-2-yl)-2-((S)-2-(2-(4-(guanidinomethyl)phenyl)acetamido)-4-(guanidinooxy)butanamido)-3,3-dimethylbutanamide

1. Bestle D, et al. Life Sci Alliance. 2020 Jul 23;3(9):e202000786.

2. Pászti-Gere E, et al. Biomed Pharmacother. 2022 Jul;151:113124.

3. Lange RW, et al. J Med Chem. 2025 Nov 30. doi: 10.1021/acs.jmedchem.5c02157.