Chemical Structure : MI-2-2 hydrochloride
CAS No.:
2308531-06-6
MI-2-2 hydrochloride
(menin-MLL inhibitor)
Catalog No. : PC-62484Not For Human Use, Lab Use Only.
MI-2-2 hydrochloride is a potent inhibitor of the menin-MLL interaction that binds to menin with low nanomolar affinity (Kd=22 nM).
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6248401
Biological Activity
MI-2-2 hydrochloride is a potent inhibitor of the menin-MLL interaction that binds to menin with low nanomolar affinity (Kd=22 nM).
Physicochemical Properties
M.Wt
451.955
Formula
C17H21ClF3N5S2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
4-(4-(5,5-Dimethyl-4,5-dihydrothiazol-2-yl)piperazin-1-yl)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidine hydrochloride
References
1. Arkin MR, et al. Chem Biol
2. Shi A, et al. Blood
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