MI-888 | MDM2 inhibitor | Probechem Biochemicals

Chemical Structure : MI-888

Catalog No.: PC-27559Not For Human Use, Lab Use Only.

MI-888 is an orally active MDM2 inhibitor with Ki of 0.44 nM, inhibit the MDM2-p53 interaction.

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Biological Activity

MI-888 is an orally active MDM2 inhibitor with Ki of 0.44 nM, inhibit the MDM2-p53 interaction.

M.Wt	548.48
Formula	C28H32Cl2FN3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2'S,3R,4'S,5'R)-6-Chloro-4'-(3-chloro-2-fluorophenyl)-N-(cis-3-hydroxy-3-methylcyclobutyl)-2'-neopentyl-2-oxospiro[indoline-3,3'-pyrrolidine]-5'-carboxamide

1. Zhao Y, et al. J Med Chem. 2013 Jul 11;56(13):5553-61.