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MIF inhibitor 4-IPP

Chemical Structure : MIF inhibitor 4-IPP

CAS No.: 41270-96-6

MIF inhibitor 4-IPP

Catalog No.: PC-25150Not For Human Use, Lab Use Only.

MIF inhibitor 4-IPP is a specific, irreversible, suicide substrate inhibitor of macrophage migration inhibitory factor (MIF).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MIF inhibitor 4-IPP is a specific, irreversible, suicide substrate inhibitor of macrophage migration inhibitory factor (MIF).
4-IPP has IC50 of as 10 times lower than that of ISO-1.
4-IPP inhibits MIF-dependent catalysis and lung adenocarcinoma cell migration and anchorage independent growth.

Physicochemical Properties

M.Wt 282.08
Formula C10H7IN2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-iodo-6-phenylpyrimidine

References

1. Winner M, et al. Cancer Res. 2008 Sep 15;68(18):7253-7.

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