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MIPS2712

Chemical Structure : MIPS2712

CAS No.: 2101814-45-1

MIPS2712

Catalog No.: PC-25475Not For Human Use, Lab Use Only.

MIPS2712 is a potent, selective, covalent, irreversible antagonist of A1 adenosine receptor (A1AR)with pKB value of 8.0, >100-fold selective for the A1AR over the A2AAR.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MIPS2712 is a potent, selective, covalent, irreversible antagonist of A1 adenosine receptor (A1AR)with pKB value of 8.0, >100-fold selective for the A1AR over the A2AAR.

Physicochemical Properties

M.Wt 517.60
Formula C24H31N5O6S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-((3-(8-cyclohexyl-2,6-dioxo-1-propyl-1,2,6,7-tetrahydro-3H-purin-3-yl)propyl)carbamoyl)benzenesulfonic acid

References

1. Glukhova A, et al. Cell. 2017 Feb 23;168(5):867-877.e13.

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