MJN228 |CAS:459168-97-9 Probechem Biochemicals

Chemical Structure : MJN228

CAS No.: 459168-97-9

MJN228 (MJN-228)

Catalog No.: PC-62671Not For Human Use, Lab Use Only.

MJN228 is a selective ligand for the lipid-binding protein nucleobindin 1 (NUCB1) with IC50 of 3.3 uM (blocks AEA-DA probe labeling of NUCB1).

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Biological Activity

MJN228 is a selective ligand for the lipid-binding protein nucleobindin 1 (NUCB1) with IC50 of 3.3 uM (blocks AEA-DA probe labeling of NUCB1).
MJN228 shows no affinity for other arachidonoyl probe-protein interactions in HEK293T cell lysate.
MJN228 is a probe used to elucidate the role of NUCB1 in lipid metabolic pathways in cells.

Physicochemical Properties

M.Wt	364.405
Formula	C20H20N4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(4-methyl-1-piperazinyl)(5-nitro-3-phenyl-1H-indol-2-yl)-methanone

References

1. Niphakis MJ, et al. Cell. 2015 Jun 18;161(7):1668-80.

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MJN228 (MJN-228)

Biological Activity

Physicochemical Properties

References

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