Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Antibiotics and Antivirals-Filovirus-MK-0608
MK-0608

Chemical Structure : MK-0608

CAS No.: 443642-29-3

MK-0608 (MK 0608;MK0608;2'-C-Methyl-7-deaza-adenosine;7DMA)

Catalog No.: PC-60960Not For Human Use, Lab Use Only.

MK-0608 is a nucleoside analogue that shows potent inhibition for replication of several mosquito-borne flaviviruses including DENV and ZIKV.

Packing Price Stock Quantity
5 mg $158 In stock
10 mg $248 In stock
25 mg $398 In stock
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MK-0608 is a nucleoside analogue that shows potent inhibition for replication of several mosquito-borne flaviviruses including DENV and ZIKV.
MK-0608 also inhibits viral RNA replication in the subgenomic HCV genotype 1b replicon with EC50 of 0.3 uM, inhibits ZIKV viral polymerase both in vitro and in vivo.

Physicochemical Properties

M.Wt 280.284
Formula C12H16N4O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2R,3R,4R,5R)-2-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol

References

1. Schul W, et al. J Infect Dis. 2007 Mar 1;195(5):665-74.

2. Carroll SS, et al. Antimicrob Agents Chemother. 2009 Mar;53(3):926-34.

3. Zmurko J, et al. PLoS Negl Trop Dis. 2016 May 10;10(5):e0004695.

4. Eyer L, et al. J Virol. 2017 Aug 16. pii: JVI.01028-17.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: