MK-3903 |CAS:1219737-12-8 Probechem Biochemicals

Chemical Structure : MK-3903

CAS No.: 1219737-12-8

MK-3903 (MK3903)

Catalog No.: PC-62013Not For Human Use, Lab Use Only.

MK-3903 is a potent and selective, direct and oral AMPK activator with EC50 of 9 nM.

Packing	Price	Stock
10 mg	$138	In stock
25 mg	$218	In stock
50 mg	$368	In stock
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Biological Activity

MK-3903 is a potent and selective, direct and oral AMPK activator with EC50 of 9 nM.
MK-3903 activates 10 of the 12 phosphorylated AMPK (pAMPK) complexes with EC50s of 8-40 nM.
MK-3903 improves lipid metabolism and insulin sensitization in mice.

Physicochemical Properties

M.Wt	454.91
Formula	C27H19ClN2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: 100 mM (45.5 mg/mL)
Chemical Name/SMILES	5-[(5-[1,1'-Biphenyl]-4-yl-6-chloro-1H-benzimidazol-2-yl)oxy]-2-methylbenzoic acid

References

1. Lan P, et al. J Med Chem. 2017 Nov 9;60(21):9040-9052.

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MK-3903 (MK3903)

Biological Activity

Physicochemical Properties

References

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