MK-4409 | FAAH inhibitor | Probechem Biochemicals

Chemical Structure : MK-4409

MK-4409 (MK4409, MK 4409)

Catalog No.: PC-60219Not For Human Use, Lab Use Only.

MK-4409 is a potent and selective, brain penetrant FAAH inhibitor with IC50 of 11 nM.

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Biological Activity

MK-4409 is a potent and selective, brain penetrant FAAH inhibitor with IC50 of 11 nM.
MK-4409 shows excellent efficacy in numerous preclinical models including the CFA and SNL pain models.

Physicochemical Properties

M.Wt	441.905
Formula	C22H17FN3O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-[5-[5-(5-Chloropyridin-2-yl)sulfanyl-2-(4-fluorophenyl)-1,3-oxazol-4-yl]pyridin-2-yl]propan-2-ol

References

1. Chobanian HR, et al. ACS Med Chem Lett. 2014 Apr 10;5(6):717-21.

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MK-4409 (MK4409, MK 4409)

Biological Activity

Physicochemical Properties

References

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