| Cat. No. |
Product Name |
Information |
| PC-20049 |
PF-04457845
FAAH inhibitor
|
PF-04457845 (Redafamdastat) is a highly potent, selective and covalent fatty acid amide hydrolase (FAAH) inhibitor with IC50 of 7.2 nM (human FAAH). |
| PC-49841 |
UCM1341
FAAH inhibitor
|
UCM1341 (UCM 1341) is a bivalent ligand with melatonin receptor agonist (hMT1/hMT2, pKi=9.11/8.77) and fatty acid amide hydrolase (FAAH) inhibitory activity (rFAAH IC5=0.85 nM). |
| PC-49009 |
PF-3845
FAAH inhibitor
|
PF-3845 is a potent, highly selective, covalent FAAH inhibitor with Ki of 0.23 uM, highly selective for FAAH in the brain. |
| PC-47021 |
ARN15381
FAAH inhibitor/D3 agonist
|
ARN15381 is a potent, multitarget FAAH inhibitor/D3 partial agonist with low nanomolar range activity, decreases nicotine self-administration in male rats. |
| PC-38511 |
ARN272
FLAT inhibitor
|
ARN272 (ARN-272) is a specific, competitive FAAH-like anandamide transporter (FLAT) inhibitor, antagonizes [3H]-anandamide binding to purified FLAT (IC50=1.8 uM) and inhibits [3H]-anandamide accumulation in FLAT-expressing HEK293 cells with IC50 of 3 uM. |
| PC-72178 |
PKM-833
FAAH inhibitor
|
PKM-833 (PKM833) is a potent, selective, and orally active FAAH inhibitor with IC50 of 8.8 and 10 nM against human and rat FAAH, respectively. |
| PC-38094 |
URB937
FAAH inhibitor
|
URB937 (URB 937) is a potent, peripherally restricted FAAH inhibitor with IC50 of 26.8 nM. |
| PC-63423 |
JNJ-40413269
FAAH inhibitor
|
JNJ-40413269 is a potent, selective, blood brain barrier (BBB) penetrant FAAH inhibitor with IC50 of 5.3 and 6.3 nM for hFAAH and rFAAH, respectively. |
| PC-63017 |
LY2318912
Anandamide transporter inhibitor
|
LY2318912 is a potent, competitive, small molecule inhibitor of anandamide uptake with IC50 of 7.27 nM, shows high affinity against anandamide transporter binding site with Kd of 7.62 nM. |
| PC-62533 |
SSR411298
FAAH inhibitor
|
SSR411298 is a highly selective, brain penetrant and orally-active inhibitor of FAAH with IC50 of 62.5 nM (mouse brain FAAH). |
| PC-60985 |
ASP 8477
FAAH inhibitor
|
ASP8477 is a novel potent, highly selective fatty acid amide hydrolase (FAAH) inhibitor with IC50 of 0.99, 1.65 and 57.3 nM for human FAAH-1, FAAH-1 (P129T) and FAAH-2, respectively. |
| PC-60706 |
SA57
FAAH/MAGL inhibitor
|
SA57a is a highly potent and selective dual FAAH/MAGL inhibitor with IC50 of 1-3 nM against FAAH, inhibits mouse (IC50=410 nM) and human (IC50=1.4 uM) MAGL. |
