SSR411298 | FAAH inhibitor | Probechem Biochemicals

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Chemical Structure : SSR411298

SSR411298 (SSR-411298)

Catalog No.: PC-62533Not For Human Use, Lab Use Only.

SSR411298 is a highly selective, brain penetrant and orally-active inhibitor of FAAH with IC50 of 62.5 nM (mouse brain FAAH).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SSR411298 is a highly selective, brain penetrant and orally-active inhibitor of FAAH with IC50 of 62.5 nM (mouse brain FAAH).
SSR411298 potently increases hippocampal levels of AEA, OEA and PEA in mice.
SSR411298 produces robust antidepressant-like activity in the rat forced-swimming test and in the mouse chronic mild stress models.

Physicochemical Properties

M.Wt	402.447
Formula	C21H26N2O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-amino-2-oxoethyl (3-((2r,5r)-5-(6-methoxynaphthalen-1-yl)-1,3-dioxan-2-yl)propyl)carbamate

References

1. Griebel G, et al. Sci Rep. 2018 Feb 5;8(1):2416.

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SSR411298 (SSR-411298)

Biological Activity

Physicochemical Properties

References

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