Catalog No.: PC-60706Not For Human Use, Lab Use Only.
SA57a is a highly potent and selective dual FAAH/MAGL inhibitor with IC50 of 1-3 nM against FAAH, inhibits mouse (IC50=410 nM) and human (IC50=1.4 uM) MAGL.
SA57a is a highly potent and selective dual FAAH/MAGL inhibitor with IC50 of 1-3 nM against FAAH, inhibits mouse (IC50=410 nM) and human (IC50=1.4 uM) MAGL.
SA57 also inhibits the 2-AG hydrolases MAGL and ABHD6, but not other brain serine hydrolases.
SA57 produces antiwithdrawal effects in morphine-dependent mice, and does not elicit any cannabimimetic side effects.
