Chemical Structure : MK-8722
CAS No.:
1394371-71-1
MK-8722
(MK8722)
Catalog No. : PC-60137Not For Human Use, Lab Use Only.
MK-8722 is a potent, selective, allosteric pan-AMPK activator with EC50 of 1-60 nM for all 12 mammalian AMPK isoforms.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6013701
Biological Activity
MK-8722 is a potent, selective, allosteric pan-AMPK activator with EC50 of 1-60 nM for all 12 mammalian AMPK isoforms.
Physicochemical Properties
M.Wt
449.891
Formula
C24H20ClN3O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(3R,3aR,6R,6aR)-6-((5-([1,1'-Biphenyl]-4-yl)-6-chloro-1H-imidazo[4,5-b]pyridin-2-yl)oxy)hexahydrofuro[3,2-b]furan-3-ol
References
1. Myers RW, et al. Science.
2. Danqing Feng, et al. ACS Med. Chem. Lett.
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