Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

You are here:Home-Chemical Inhibitors & Agonists-Proteasome/Ubiquitin-p97/VCP-ML-241 hydrochloride
ML-241 hydrochloride

Chemical Structure : ML-241 hydrochloride

CAS No.: 2070015-13-1

ML-241 hydrochloride (ML241 hydrochloride;ML 241 hydrochloride)

Catalog No.: PC-45719Not For Human Use, Lab Use Only.

ML241 hydrochloride is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM).

Packing Price Stock Quantity
25 mg $158 In stock
50 mg $248 In stock
100 mg $398 In stock
200 mg Get quote
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ML241 hydrochloride is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM).
ML241 blocks degradation of p97-dependent proteasome substrate with an IC50 of 3.5 uM.
ML241 induces caspases 3 and 7 and potently blocks proliferation in HCT15 and SW403 cells.

Physicochemical Properties

M.Wt 408.9238
Formula C23H25ClN4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 34 mg/mL

Chemical Name/SMILES

4-Quinazolinamine, 2-(2,3-dihydro-4H-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydro-N-(phenylmethyl)-,hydrochloride

References

1. Chou TF, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

2. Chou TF, et al. ChemMedChem. 2013 Feb;8(2):297-312.

3. Fang CJ, et al. ChemMedChem. 2015 Jan;10(1):52-6.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: