ML-B01

Chemical Structure : ML-B01

Catalog No.: PC-24887Not For Human Use, Lab Use Only.

ML-B01 is an ipatasertib analog and selective Akt inhibitor with IC50 of 2.0 nM and 136 nM for Akt1 and PKA respectively.

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Biological Activity

ML-B01 is an ipatasertib analog and selective Akt inhibitor with IC50 of 2.0 nM and 136 nM for Akt1 and PKA respectively.

M.Wt	476.45
Formula	C24H31Cl2N5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-1-(4-((5R,7R)-7-chloro-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-2-(4-chlorophenyl)-3-(isopropylamino)propan-1-one

1. Yan Wu, et al. Nat Chem Biol. 2025 Feb 11. doi: 10.1038/s41589-025-01846-y.