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ML090

Chemical Structure : ML090

CAS No.: 531-46-4

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ML090 (CCG-44699;Fluoflavin;NSC 179821)

Catalog No.: PC-36153Not For Human Use, Lab Use Only.

ML090 (ML-090, CCG-44699, Fluoflavin, NSC 179821) is a potent, selecitve inhibitor of NADPH oxidase 1 (NOX1) with IC50 of 90 nM, displays no significant activities against NOX2, 3 and 4 (IC50>10 uM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ML090 (ML-090, CCG-44699, Fluoflavin, NSC 179821) is a potent, selecitve inhibitor of NADPH oxidase 1 (NOX1) with IC50 of 90 nM, displays no significant activities against NOX2, 3 and 4 (IC50>10 uM).

Physicochemical Properties

M.Wt 234.3
Formula C14H10N4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5,12-dihydro-quinoxalino[2,3-b]quinoxaline

References

1. Carmo LSD, et al. J Clin Invest. 2019 Mar 18;130. pii: 127682.

2. Smith RM, et al. Clin Exp Pharmacol Physiol. 2015 Aug;42(8):860-4.

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