ML307 | Ubc13 inhibitor | Probechem Biochemicals

Chemical Structure : ML307

ML307 (ML-307)

Catalog No.: PC-38264Not For Human Use, Lab Use Only.

ML307 is a potent, sub-micromolar (IC50=781 nM), first-in-class, small molecule inhibitor of Ubc13 enzyme activity, >128-fold selective against Caspase-3 and Bfl-1.

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Biological Activity

ML307 is a potent, sub-micromolar (IC50=781 nM), first-in-class, small molecule inhibitor of Ubc13 enzyme activity, >128-fold selective against Caspase-3 and Bfl-1.

Physicochemical Properties

M.Wt	522.094
Formula	C28H36ClN7O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N-((1-(3-chlorobenzyl)piperidin-4-yl)methyl)-1-(6,7,8,9-tetrahydropyrido[1,2-e]purin-4-yl)piperidine-3-carboxamide

References

1. Robert Ardecky, et al. Probe Reports from the NIH Molecular Libraries Program [Internet]. 2012.

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ML307 (ML-307)

Biological Activity

Physicochemical Properties

References

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