| Cat. No. |
Product Name |
Information |
| PC-21370 |
ETC-6152
UBE2T inhibitor
|
ETC-6152 is a potent, specific and covalent E2 ubiquitin ligase UBE2T inhibitor with IC50 of 0.22 uM, targets Cys86 of UBE2T and shows selectivity on UBE2T over UBE2K. |
| PC-73071 |
UBE2T/FANCL inhibitor UC2
UBE2T/FANCL inhibitor UC2
|
UBE2T/FANCL inhibitor UC2 (UC2) is a specific small-molecule inhibitor of UBE2T/FANCL-mediated FANCD2 monoubiquitylation, inhibits the ubiquitylation of GST-FANCL RINGwith IC50 of 14.8 uM in HTRF ubiquitylation assay. |
| PC-72869 |
UC-764865
UBE2N inhibitor
|
UC-764865 (UC764865) is a small-molecule inhibitor that targeted ubiquitin-conjugating enzyme UBE2N active site. |
| PC-72868 |
UC-764864
UBE2N inhibitor
|
UC-764864 (UC764864) is a small-molecule inhibitor that targeted ubiquitin-conjugating enzyme UBE2N active site. |
| PC-72231 |
DI-1859
DCN1 inhibitor
|
DI-1859 (DI 1859) is a potent, selective and covalent DCN1 inhibitor with IC50 of 4.6 nM and Ki of <1 nM, does not bind to DCN3. |
| PC-72230 |
DI-1548
DCN1 inhibitor
|
DI-1548 (DI 1548) is a potent, selective and covalent DCN1 inhibitor with IC50 of 4.6 nM and Ki of <1 nM, does not bind to DCN3. |
| PC-72140 |
UbcH5c inhibitor DHPO
UbcH5c inhibitor
|
UbcH5c inhibitor DHPO (Britanin, NSC145913) is a small molecule UbcH5c inhibitor, directly targets UbcH5c with KD of 37.5 uM. |
| PC-72009 |
TG-6304
DCN3 inhibitor
|
TG-6304 (TG6304) is a first-in-class, potent, highly selective, cell-permeable DCN3 inhibitor with Ki of 35 nM, does not bind to DCN1 at 30 uM. |
| PC-38264 |
ML307
Ubc13 inhibitor
|
ML307 is a potent, sub-micromolar (IC50=781 nM), first-in-class, small molecule inhibitor of Ubc13 enzyme activity, >128-fold selective against Caspase-3 and Bfl-1. |
| PC-36111 |
WS-383
DCN1 inhibitor
|
WS-383 (WS383) is a highly potent, selective, and cellular active inhibitor of DCN1-UBC12 interaction with IC50 of 11 nM. |
| PC-36110 |
WS-383 hydrochloride
DCN1 inhibitor
|
WS-383 hydrochloride (WS383) is a highly potent, selective, and cellular active inhibitor of DCN1-UBC12 interaction with IC50 of 11 nM. |
| PC-35686 |
NSC697923
Ubc13 inhibitor
|
NSC697923 (NSC 697923) is a small molecule that specifically inhibits the activity of the ubiquitin-conjugating (E2) enzyme Ubc13 (UBE2N)-Uev1A. |
