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Chemical Structure : ML337
CAS No.: 1443118-44-2
Catalog No.: PC-22905Not For Human Use, Lab Use Only.
ML337 is a potent, selective and brain-penetrant negative allosteric modulator of mGlu3 with IC50 of 593 nM, with no effect on mGlu2 (IC50>30 uM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $118 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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ML337 is a potent, selective and brain-penetrant negative allosteric modulator of mGlu3 with IC50 of 593 nM, with no effect on mGlu2 (IC50>30 uM).
| M.Wt | 353.39 | |
| Formula | C21H20FNO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
[2-Fluoro-4-[2-(4-methoxyphenyl)ethynyl]phenyl][(3R)-3-hydroxy-1-piperidinyl]methanone |
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1. Wenthur CJ, et al. J Med Chem. 2013 Jun 27;56(12):5208-12.
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