ML337 | mGlu3 NAM | Probechem Biochemicals

Chemical Structure : ML337

CAS No.: 1443118-44-2

Catalog No.: PC-22905Not For Human Use, Lab Use Only.

ML337 is a potent, selective and brain-penetrant negative allosteric modulator of mGlu3 with IC50 of 593 nM, with no effect on mGlu2 (IC50>30 uM).

Packing	Price	Stock
5 mg	$118	In stock
10 mg	$188	In stock
25 mg	$328	In stock
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Biological Activity

ML337 is a potent, selective and brain-penetrant negative allosteric modulator of mGlu3 with IC50 of 593 nM, with no effect on mGlu2 (IC50>30 uM).

M.Wt	353.39
Formula	C21H20FNO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	[2-Fluoro-4-[2-(4-methoxyphenyl)ethynyl]phenyl][(3R)-3-hydroxy-1-piperidinyl]methanone

1. Wenthur CJ, et al. J Med Chem. 2013 Jun 27;56(12):5208-12.