ML339 | CXCR6 antagonist | Probechem Biochemicals

Chemical Structure : ML339

ML339 (ML 339)

Catalog No.: PC-38130Not For Human Use, Lab Use Only.

ML 339 is a potent and selective hCXCR6 antagonist (IC50 = 140 nM), 100-fold less active at the murine CXCR6 receptor (IC50 = 18 uM).

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Biological Activity

ML 339 is a potent and selective hCXCR6 antagonist (IC50 = 140 nM), 100-fold less active at the murine CXCR6 receptor (IC50 = 18 uM)。
ML 339 exhibits selectivity over CXCR5, CXCR4, CCR6 and APJ receptors.

Physicochemical Properties

M.Wt	502.008
Formula	C26H32ClN3O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 1 Month
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Solubility	10 mM in DMSO
Chemical Name/SMILES	9-Azabicyclo[3.3.1]nonane-9-acetamide, N-(2-chlorophenyl)-3-[(3,4,5-trimethoxybenzoyl)amino]-, (3-exo)-

References

1. Satyamaheshwar Peddibhotla, et al. Bioorg Med Chem Lett. 2020 Feb 15;30(4):126899.

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ML339 (ML 339)

Biological Activity

Physicochemical Properties

References

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