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Chemical Structure : ML354
Catalog No.: PC-62125Not For Human Use, Lab Use Only.
ML354 (VU0099704) is a novel potent and selective PAR4 antagonist with IC50 of 140 nM, displays 71-fold selectivity versus PAR-1.
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ML354 (VU0099704) is a novel potent and selective PAR4 antagonist with IC50 of 140 nM, displays 71-fold selectivity versus PAR-1。
ML354 (VU0099704) also displays improved physical properties and is very amenable to future medicinal chemistry development.
| M.Wt | 282.29 | |
| Formula | C16H14N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Wen W, et al. Bioorg Med Chem Lett. 2014 Oct 1;24(19):4708-13.
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