Chemical Structure : ML359
CAS No.: 1069858-99-6
Catalog No.: PC-62115Not For Human Use, Lab Use Only.
ML359 is a small molecule, specific inhibitor of Protein disulfide isomerase (PDI) with IC50 of 250 nM.
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10 mg | $358 | In stock | |
25 mg | $548 | In stock | |
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ML359 is a small molecule, specific inhibitor of Protein disulfide isomerase (PDI) with IC50 of 250 nM.
ML359 displays >100-fold selectivity over other thiol isomerases (Erp5, Thioredoxin, Thioredoxin reductase).
ML359 shows no cytotoxicity in three human cell lines, and some activity in inhibiting platelet aggregation in vitro.
M.Wt | 417.93 | |
Formula | C23H28ClNO4 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: 100 mg/mL |
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Chemical Name/SMILES |
Ethyl 1-(3-chloro-4-hydroxybenzyl)-4-(2-phenoxyethyl)piperidine-4-carboxylate |
1. Khodier C, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
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