You are here:Home-Chemical Inhibitors & Agonists-Others-Protein Disulfide Isomerase (PDI)-ML359
ML359

Chemical Structure : ML359

CAS No.: 1069858-99-6

ML359 (ML 359)

Catalog No.: PC-62115Not For Human Use, Lab Use Only.

ML359 is a small molecule, specific inhibitor of Protein disulfide isomerase (PDI) with IC50 of 250 nM.

Packing Price Stock Quantity
10 mg $258 In stock
25 mg $428 In stock
50 mg $728 In stock
100 mg $1280 In stock
500 mg Get quote
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ML359 is a small molecule, specific inhibitor of Protein disulfide isomerase (PDI) with IC50 of 250 nM.
ML359 displays >100-fold selectivity over other thiol isomerases (Erp5, Thioredoxin, Thioredoxin reductase).
ML359 shows no cytotoxicity in three human cell lines, and some activity in inhibiting platelet aggregation in vitro.

Physicochemical Properties

M.Wt 417.93
Formula C23H28ClNO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: 100 mg/mL

Chemical Name/SMILES

Ethyl 1-(3-chloro-4-hydroxybenzyl)-4-(2-phenoxyethyl)piperidine-4-carboxylate

References

1. Khodier C, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: