| Cat. No. |
Product Name |
Information |
| PC-21467 |
E64FC26
pan PDI inhibitor
|
E64FC26 is a potent, pan-style PDI (protein disulfide isomerase) inhibitor with IC50 of 1.9 uM (PDIA1), also inhibits all other members of the PDI family including PDIA3, PDIA4, TXNDC5, and PDIA6. |
| PC-49720 |
AA132
UPR activator
|
AA132 (AA-132) is a small molecule activator of UPR signaling, covalently modifies a subset of ER protein disulfide isomerases (PDIs), activates global UPR signaling through a mechanism analogous to that of AA147. |
| PC-63459 |
KSC-34
PDIA1 inhibitor
|
KSC-34 (PDIA1 inhibitor KSC-34) is a potent, selective protein disulfide isomerase A1 (PDIA1) inhibitor, 30-fold selectivity for the A-site over the A' site. |
| PC-62115 |
ML359
PDI inhibitor
|
ML359 is a small molecule, specific inhibitor of Protein disulfide isomerase (PDI) with IC50 of 250 nM. |
| PC-62113 |
Juniferdin
PDI inhibitor
|
Juniferdin is a small molecule, potent Protein disulfide isomerase (PDI) inhibitor with IC50 of 156 nM, inhibits PDI-mediated reduction of HIV-1 envelope glycoprotein gp120. |
| PC-61520 |
16F16
PDI inhibitor
|
16F16 is a small molecule protein disulfide isomerase (PDI) inhibitor that suppress apoptosis induced by misfolded proteins. |
| PC-70360 |
PACMA31
PDI inhibitor
|
PACMA31 is an orally active, irreversible inhibitor of protein disulfide isomerase (PDI), forming a covalent bond with the active site cysteines of PDI. |
| PC-70321 |
LOC14
PDI inhibitor
|
LOC14 is a small molecule reversible Protein disulfide isomerase (PDI) inhibitor with Kd of 62 nM. |
| PC-42153 |
CCF642
PDI inhibitor
|
CCF642 (CCF 642) is a novel covalent protein disulfide isomerase (PDI) inhibitor with IC50 of 2.9 uM, shows antimyeloma activity. |
| PC-25630 |
P4HB inhibitor 2b
P4HB inhibitor
|
P4HB inhibitor 2b is a tau-aggregate clearing compound (EC50=0.11 uM) that covalently targets protein disulfide isomerase 1 (P4HB, PDIA1), shows maximal tau clearance of >90% with no observable cytotoxicity. |
| PC-25629 |
P4HB inhibitor 2a
P4HB inhibitor
|
P4HB inhibitor 2a is a tau-aggregate clearing compound (EC50=0.18 uM) that covalently targets protein disulfide isomerase 1 (P4HB, PDIA1), shows maximal tau clearance of 91% with no observable cytotoxicity. |
