Chemical Structure : ML390
CAS No.:
2029049-79-2
ML390
(ML 390;ML-390)
Catalog No. : PC-42227Not For Human Use, Lab Use Only.
ML390 is a potent DHODH inhibitor that causes myeloid differentiation in murine (ER-HoxA9) and human (U937 and THP1) AML models (ED50=2 uM).
Packing Price Stock Quantity 5 mg $148 In stock 0 1 2 3 4 5 10 mg $218 In stock 0 1 2 3 4 5 25 mg $358 In stock 0 1 2 3 4 5 50 mg $548 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4222701
Biological Activity
ML390 is a potent DHODH inhibitor that causes myeloid differentiation in murine (ER-HoxA9) and human (U937 and THP1) AML models (ED50=2 uM).
Physicochemical Properties
M.Wt
406.3983
Formula
C21H21F3N2O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 27 mg/mL
Chemical Name/SMILES
(R)-N-(3-oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide
References
1. Sykes DB, et al. Cell.
2. Lewis TA, et al. ACS Med Chem Lett.
3. Sykes DB, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
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